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Beagle (Dog) Walking with Owner in the Park

Vagus Nerve Stimulation (VNS)

A Medication-Sparing Option for Selected Dogs

Evidence in humans, where VNS is a standard of care, and small veterinary studies suggest that some dogs with drug-resistant epilepsy can have meaningful reductions in seizure burden or even seizure freedom. It is a good option when medications are not working or tolerated, however, not all dogs respond and the benefit may build gradually over months or even years.

A Brown/White Beagle (Dog) Being Examined by a Veterinarian

What is VNS?

Vagus nerve stimulation uses gentle, intermittent electrical pulses delivered to the left vagus nerve in the neck. The vagus nerve carries signals to brain regions involved in seizure control. Repeated stimulation can alter brain-network activity and neurotransmitter signaling in ways that may make seizures less likely.

The Milo VNS system is designed specifically for dogs. It combines a very small, implanted pulse generator with a rechargeable Smart Collar that wirelessly powers and communicates with the implant. An app allows therapy status and seizures to be tracked, while the veterinary neurologist can monitor and adjust therapy remotely.

A Pug (Dog) with Two Veterinarians

How VNS may help?

VNS may help by modulating brain networks involved in seizure control, changing neurotransmitter signaling, and reducing the synchronized electrical activity that contributes to seizures. These effects develop gradually, which is why improvement may continue to build over months or longer rather than immediately.